![]() GREML: estimating the proportion of variance in a phenotype explained by all SNPs (i.e., the SNP-based heritability).Estimating the inbreeding coefficients of individuals in GWAS data.GRM: estimating genetic relationships among individuals from SNP data. ![]() Heritability, genetic correlation, and phenotype prediction GCTA currently supports the following analyses. GCTA (Genome-wide Complex Trait Analysis) is a software package initially developed to estimate the proportion of phenotypic variance explained by all genome-wide SNPs for a complex trait but has been greatly extended for many other analyses of data from genome-wide association studies (GWASs).
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